Who This Guide Is For

This guide is intended for procurement teams, process chemists, medicinal chemistry groups, custom synthesis companies, and distributors sourcing specialty organic boronic acids. It is also useful for buyers who need to compare suppliers without relying only on a product title or a quoted price. I have structured the evaluation around the practical questions that normally affect a purchase decision.

4-(Hydroxymethyl)phenylboronic acid may be purchased for laboratory research, route development, small-scale process work, or planned commercial synthesis. The appropriate grade, package size, testing scope, and lead time can differ considerably between these use cases. For that reason, I recommend defining the intended application before requesting a final quotation.

Basic Chemical Identity and Context

4-(Hydroxymethyl)phenylboronic acid is an aryl boronic acid in which a hydroxymethyl substituent is positioned on the aromatic ring. The commonly associated molecular formula is C₇H₉BO₃, with a calculated molecular weight of approximately 151.96 g/mol. The listed CAS number is 59016-93-2.

The boronic acid functionality is the key reactive feature for many synthetic applications, while the hydroxymethyl group provides an additional functional handle. Depending on the reaction design, this combination can support further transformations, protecting-group strategies, linker preparation, or the development of more complex aromatic intermediates. Actual performance should be confirmed in the buyer’s own reaction system because solvent, catalyst, substrate, water content, and handling conditions can influence results.

Identity Checks Before Purchase

• Confirm the product name and CAS number: 4-(Hydroxymethyl)phenylboronic acid, CAS 59016-93-2.
• Check that the molecular formula and molecular weight shown on the specification sheet are consistent with the intended structure.
• Review the structural representation to distinguish the para-substituted compound from positional isomers.
• Request a current certificate of analysis for the relevant production lot.
• Confirm whether the material is supplied as the free boronic acid and whether any special storage statement applies.

Specification Options Buyers Should Review

There is no single specification package that suits every buyer. A discovery laboratory may primarily need identity confirmation and a practical purity target, while a process-development customer may require tighter impurity information, batch consistency, and documented packaging controls. I recommend asking suppliers to state each test method and acceptance criterion rather than accepting a generic “high purity” description.

Buyers should avoid treating a quoted purity number as a complete quality assessment. The analytical technique, sample preparation, reporting basis, and impurity profile can be equally important. If the compound will enter a regulated or tightly controlled development process, I suggest agreeing on the specification before production rather than attempting to revise it after shipment.

Matching the Material to the Application

The principal application area is organic synthesis involving aryl boronic acids. Chemists may evaluate this compound as a building block for carbon-carbon bond-forming reactions, including palladium-catalyzed coupling routes, although the suitability of any specific reaction must be established experimentally. The hydroxymethyl substituent may also be retained for later functionalization or converted according to the route design.

For early-stage research, a small package may be appropriate because the development route can change quickly. For scale-up, the priority usually shifts toward reproducible assay, controlled impurity levels, stable packaging, and a realistic replenishment plan. I recommend sharing the intended reaction stage and approximate annual demand with the supplier so that the quotation reflects the actual sourcing requirement.

Important Application Questions

1. Will the boronic acid be used directly, or will the hydroxymethyl group require protection?
2. Is the material intended for screening, route development, pilot work, or repeated manufacturing supply?
3. Could water, residual solvent, or trace metals influence the reaction or downstream purification?
4. Does the receiving site require a specific container type, label format, or document set?
5. Is a reserve sample needed for identity or stability comparison?

A Practical Supplier Selection Framework

I evaluate suppliers using four connected criteria: technical fit, quality transparency, supply capability, and communication. A supplier should be able to explain what is routinely controlled, what is tested on each batch, and which documents can be provided before shipment. Clear answers are more valuable than broad claims that cannot be linked to a specification or lot record.

1. Confirm Technical Fit

Start with the exact identity and intended grade. Ask for the molecular formula, molecular weight, appearance, purity method, storage guidance, and a representative certificate of analysis. If the product is for a sensitive route, request discussion of relevant impurities rather than relying only on a headline assay value.

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2. Review Quality Documentation

At a minimum, most B2B buyers should review a safety data sheet and a lot-specific certificate of analysis. Depending on internal procedures, additional documents may include a specification sheet, residual solvent information, elemental analysis, or a statement concerning production and packaging controls. I recommend checking that the lot number on the certificate matches the container and shipping documents.

3. Plan Quantity, MOQ, and Lead Time

Minimum order quantity and lead time can vary by package size, stock status, production schedule, and destination. A buyer should request these details in writing and distinguish between an in-stock dispatch time and a made-to-order production timeline. For planning purposes, communicate the required quantity in grams or kilograms, the requested delivery window in days, and whether split delivery is acceptable.

Price should be assessed together with testing, packaging, transport, and supply continuity. A lower unit price may not be advantageous if the documentation is incomplete or the delivery schedule does not support the project. Conversely, a slightly higher quotation may be reasonable when it includes more suitable packaging, additional testing, or a better-defined replenishment plan.

Packaging, Storage, and Handling Considerations

Buyers should follow the supplier’s current safety data sheet and product-specific handling instructions. The receiving laboratory or warehouse should assess exposure controls, labeling, segregation, and any moisture-related precautions required for the material. I do not recommend assuming a universal storage condition without reviewing the documentation supplied for the actual product lot.

For international supply, packaging should be matched to the quantity and transport route. The purchase order should identify the net quantity, container configuration, outer packaging, label language, and document requirements. A defined packaging plan helps reduce avoidable delays during customs review, warehouse receipt, and internal quality release.

Common Buying Mistakes

• Ordering by chemical name alone without confirming CAS number and structure.
• Comparing suppliers only by price without comparing analytical methods and documentation.
• Assuming that a research package and a scale-up package have identical quality controls.
• Failing to communicate the required delivery date, destination, or import documentation.
• Waiting until the final reaction campaign to investigate replenishment lead time.

Another frequent mistake is requesting a quotation without explaining the expected use. A supplier cannot reasonably recommend package size, testing depth, or production timing if the requirement is limited to a product name and a quantity. A concise technical inquiry generally produces a more useful commercial response.

How Maison Chemical Can Support Your Evaluation

At Maison Chemical, I recommend treating 4-(Hydroxymethyl)phenylboronic acid CAS 59016-93-2 as a complete sourcing project rather than a simple catalog purchase. We can discuss identity confirmation, target quantity, application stage, required documentation, packaging preferences, destination, and timing before preparing a quotation. This approach helps align the commercial offer with the buyer’s actual technical and supply requirements.

When requesting information, please provide the desired quantity, purity expectation, delivery location, intended use, and any internal quality requirements. If you need a specific certificate format, pre-shipment documents, or a defined package configuration, include those details at the inquiry stage. Availability, MOQ, lead time, and testing scope should be confirmed for the current order because they may depend on production and logistics conditions.

Key Takeaways

• 4-(Hydroxymethyl)phenylboronic acid CAS 59016-93-2 is an aromatic boronic acid with a hydroxymethyl substituent and an approximate molecular weight of 151.96 g/mol.
• Identity confirmation should include the CAS number, molecular formula, structure, and lot-specific analytical documentation.
• Application fit depends on the reaction route, impurity sensitivity, water tolerance, and whether the hydroxymethyl group will be retained or modified.
• Specification, packaging, MOQ, lead time, and documentation should be agreed before purchase, especially for scale-up or repeated supply.
• A complete inquiry enables Maison Chemical to provide a more relevant supply recommendation and quotation.

Conclusion: A Practical Next Step for Buyers

The best way to buy 4-(Hydroxymethyl)phenylboronic acid CAS 59016-93-2 is to verify identity first, define the application and quality needs, then compare suppliers on documentation, consistency, packaging, and delivery capability. The compound can be a useful synthetic intermediate, but its suitability should be confirmed in the buyer’s own process rather than inferred from the name alone. Careful specification alignment is especially important when moving from laboratory quantities to ongoing production supply.

To begin, send Maison Chemical your required quantity, target specification, destination, documentation needs, and requested delivery schedule. I can then help organize the technical and commercial information needed for a clear B2B evaluation of this product.